This is an old family secret, and I just found this out recently, and it almost broke my heart. My mother said to me, 'I had never told you this, but God, you were an ugly baby'.

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Joining 'ER,' I felt like that kid who got the golden ticket in 'Charlie and the Chocolate Factory.' I've been offered chocolate bars all these years, but there had been no golden ticket. Just the...

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I've been been on the cover of TV Guide, on every single talk and entertainment show except Letterman. It's interesting being older and dealing with this kind of success. I'm more appreciative of it...

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I once dated someone who worked at McDonald's. She came up and asked if I wanted a Big Mac.

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I have never been so calculating as to sing some Barry White song to get a girl. But I do think it's very romantic to cook dinner and sit around the piano at night and sing together.

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I don't want to replace anyone, especially Charlie Sheen.

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I grew up doing sitcoms and theater and even playing with the Beach Boys, where you're programmed to perform, your body gets into a rhythm and you know it has to perform.

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I think I got turned onto The Beach Boys for the first time with the 'Endless Summer' album in 1974. The power of that music still, to this day, bypasses the brain and goes straight to the heart. You...

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I started Pilates. I'm the only guy in there. They plot before I get there: 'How can we make John look ridiculous?' Because every exercise involved my legs up, like I'm in the stirrups or something.

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I'm not the guy who bursts into the room. I'm the most insecure person you'll meet if you get to know me.

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