Tip:
Highlight text to annotate it
X
My name is Lauryn Swier and the title of my poster
is "Glioma micro-environment alters T-cell priming in the cervical lymph nodes."
So, we looked at their differences and differing vaccination sites
for cancer vaccines and immunotherapy,
and we saw previously in our lab that cancer vaccines can be used to
get better outcomes, longer survival,
or tumor regression. So we're thinking,
"can we refine this a little bit more by altering where we were giving the
vaccine?"
We vaccinated in the cervical lymph nodes axillary lymph nodes and inguinal
lymph nodes.
We saw that there was improved tumor regression and increase median survival
in animals that were vaccinated in the inguinal lymph nodes.
Eventually we hope that
this can be integrated into current clinical trials, as well as future
experimental
design, to standardize the vaccination site that is the best
for survival and outcome. I initially got interested in research because
I was a home health aide for a woman who had brain cancer
and I saw all the secondary effects of how brain cancer can impact someone's
life
and I wanted to stay involved
in this issue when I got back to school. So I found a lab that dealt with
brain cancer
and I decided I want to get involved them.