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Whether it’s the the first day of school, a big interview or your wedding day - pimples
find a way of cropping up at the most inconvenient times. But why do they occur and how do we
get rid of them?
The term “pore”, it is just another way of saying “hair follicle”, and your body
is covered in them. Within the follicle is a gland that produces an oily substance called
sebum, which empties onto the skin to keep your hair and body moisturized. But if the
hair follicle becomes clogged with dead skin cells and oils, a blockage is created. Sebum
continues to be produced but it is trapped within the follicle making it become enlarged.
And this is where bacteria come into play, feeding on the dead skin and sebum which can
unfortunately lead to infection. Your immune system responds by sending blood to the area,
giving the appearance of redness and inflammation, and white blood cells come to the site too,
to clear up the infection. When the white blood cells die, they, combined with the dead
skin and sebum, create the pus filled pimple.
If the blockage occurs under the skin it creates a white bump known as a “whitehead” and
if the blockage is above the skin and black discolouration occurs it’s known as a “blackhead”.
This is a result of melanin in the dead skin cells reacting with oxygen creating a black
colour - it’s not dirt.
We get the most pimples when we are teens due to the increased amount of androgen hormones
like testosterone in our bodies at the onset of puberty. Testosterone sends the production
of sebum into overdrive, increasing the incidence of blockages. But zits can occur at any time
- often brought on by stressful events. Cortisol, the stress hormone, increases the amount of
inflammation in your body (aka more red bumps on your face) and can also suppress your immune
system, meaning your body can’t fight the bacteria that is causing the acne.
So how do we fight the war on pimples? For normal breakouts, cleaning your face to remove
excess oil which prevents pore blockage and occasionally exfoliating to remove dead skin
will help, although acne often cannot be solved this way. And it’s important to remember
that cleanliness and diet do not play a major role in acne, but rather your genetics and
hormones. Many drugs exist like benzoyl peroxide which kills specific acne causing bacteria,
salicylic acid which helps to remove dead skin blockages, retinoids which reduce sebum
production and a variety of others; though some drugs can have severe side effects. In
women, some success has been seen with oral contraceptives, which decrease the ovaries
production of androgen hormones, ultimately decreases sebum. Of course, consulting with
a doctor over which regimen is best suited to you is always best.
But new therapies and cures may be on the horizon with the help of science! By studying
individuals who do not get acne, scientists noticed something: the bacteria that typically
causes acne still exists on their skin, but it’s a different strain. It turns out that
this same bacteria with slightly different genes causes healthier skin. Knowing this,
future therapies may include a deeper look at the bacterial level, and whether or not
altering your skin microbiota could cure pimples.
We're really glad to be working in collaboration with Bill and Melinda Gates in supporting
their Annual Letter this year called “Two superpowers we wish we had”! Every year
they release a letter looking at global issues, and this year the question is: what would
your superpower for good be? Would it be to have more clean energy like Bill or more time
like Melinda, which means one thing in rich countries and something else to the world’s
poorest families. It’s a chance to enact positive change in the world – so find something
you’re passionate about and learn more about it. Check out the letter with the link in
the description, and we'll be posting our superpower ideas on instagram with #superpowerforgood.