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TCAs, or tricyclic antidepressants, are a class of drugs that were among the first developed
to treat depression. TCAs work by blocking the absorption of certain brain chemicals,
primarily serotonin and norepinephrine, and help to maintain mental balance and boosting
mood. TCAs share a few common side effects including dry mouth, blurred vision, constipation,
drowsiness and increased appetite leading to weight gain. Other side effects include
nausea, changes in sex drive, and excessive sweating. Some examples of medications in
this class are Elavil, also known as amitriptyline, and Pamelor, the brand name for nortriptyline.
Rarely, TCAs can cause serotonin syndrome, in which serotonin levels become dangerously
high. Symptoms of serotonin syndrome include anxiety, sweating, confusion, tremors, lack
of coordination and rapid heart rate. Seek immediate medical attention if you have any
of these symptoms. Anyone taking an antidepressant should be watched closely for worsening depression
or unusual behavior. If you or someone you know has suicidal thoughts when taking an
antidepressant, contact your doctor or get emergency help. It is always a good idea to
ask questions about your medication if you are unsure or if you experience something
out of the ordinary. Use this medication only as prescribed. To keep up to date with medication
information, sign up for RxWiki Notify.