Colin Kaepernick will make his 2016 preseason debut Friday night as the San Francisco 49ers host the Green Bay Packers. The quarterback missed the team's first two exhibition contests with a fatigued right throwing shoulder. Kaepernick's return to game action is a pivotal moment in his ongoing competition with Blaine Gabbert. A strong performance will help his case as Chip Kelly is yet to determine his Week 1 starter.