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Open Opera browser on your computer.
Click on the opera icon at the top of the browser.
Hover your mouse on the settings tab and select "Preferences."
Preferences dialogue box will appear.
Click on the "General" tab.
Under Startup section, click on the drop down arrow and select " start with home page".
Type in the URL of the website that you want to set as home page.
For this example i will set google.com as my home page.
Click ok to save the changes.
Now close the browser and open it again.
Now close the browser and open it again.
As you can see opera home page has been changed to google.com
This is How You Can Change Startup Page in Opera Browser.