The WHO Roadmap, published in 2011, is a comprehensive plan of control, elimination and eradication targets for 17 NTDs to be reached between 2012-2020. This document is the culmination of nearly eight years of global discussions that have reshaped the international consciousness that investment in areas outside of the “big three” diseases (malaria, HIV/AIDS and TB) can have major impact of global disease burden and morbidity.