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here's a look at what's coming up in the August 2013
issue JoVE the journal of visualized experiments
honey is an an age-old anti-aging product
and according to legend cleopatra the Queen of the Nile
bathed in honey to preserve her ageless beauty. But
did you know honey bees themselves might hold the secret
to slowing or even reversing aging? the honey bee
is an established model for studying how social and environmental factors
can affect the aging process. Nurse bees
which stay in the hive tend the growing larvae, age more slowly than forager bees
which venture out to collect nectar and pollen. our authors expand classical
experimental paradigms
with three new techniques for studying aging in honey bees;
distinguishing chronological aging from work induced senescence
reverting forager bees into nurse bees by taking them to a new hive
and quantifying aging by measuring lipofuscin
a known biomarker of cellular senescence. It smells like smoke over in the JoVE
behavior section
where we feature a method for studying the brain's response
to cigarette smoking. Our authors use photonics emission tomography
or PET to noninvasively image the dopaminergic system during smoking
they also make dopamine movies to illustrate how smoking causes dopamine
levels
to fluctuate in the striatal area the brain. Because the rise and fall
have strayed alt open mean levels contributes to addiction and withdrawal
this is a powerful technique for studying the addictive affects
up smoking. In JoVE Applied Physics
we have an article in the field microwave photonics
which studies the interaction between microwaves and optical waves.
Our authors build microwave photonic systems
based on whispering gallery modes which are waves that can travel around a
concave surface
to make the resonator our authors grind down a commercially available
crystalline optical window polish it with extremely fine particles
and verify its smoothness using interferometric measurements.
then they draw a fiber taper which couples light
in the resonator finally our authors show how to excite
whispering gallery mode this promising technology has many potential
applications in aerospace
telecommunications and other areas. In JoVE bioengineering
we build upon the classical two-dimensional cell culture
with an engineered three-dimensional tumor test system
in this biological vascularized scaffold
a metal inserts containing decellularized small intestinal submucosa
serves as a scaffold for culture in cancer cells other cell types
these can be grown statically or as a dynamic culture
in a flow bioreactor which exposes cells to shear stress
this allows a lifelike model for studying tumor development
and potential treatments. you've just had a sneak peek a few highlights from the
August 2013
issue of JoVE visit the website to see the full length
articles plus many more in JoVE the journal of visualized experiments